| 摘要 |
The invention relates to the use of IL-15 inhibiting or eliminating compounds that interfere with the binding of IL-15 to its receptor for the manufacture of a pharmaceutical composition for suppression of formation of CD4<+> memory cells of the immune system. Such inhibiting or eliminating compounds are for example anti-IL-15 antibodies, anti-IL-15R alpha antibodies, fragments of these antibodies, e.g. the Fab or F(ab')2 fragment, soluble IL-15R alpha , fusion proteins consisting of soluble IL-15R alpha , and Fc fragment, compounds, e.g. peptides, binding and/or inhibiting functional IL-15 receptor, IL-15 antisense oligonucleotides. |
