发明名称 |
Aminohydroxylation of olefins with tert-alkyl sulfonamides |
摘要 |
Tert-alkyl sulfonamides chloramine salts are used as nitrogen sources in the catalytic aminohydroxylation and/or aziridination of olefins. The tert-alkyl sulfonamides chloramine salts are close to Chloramine T with respect to their reactivity as nitrogen sources with olefins. However, unlike the tosyl sulfonyl amine group of Chloramine T, the resulting t-alkyl sulfonylamino functionalities can be easily converted to an unprotected amine under mild acidic conditions making the method a simple and cost efficient approach for producing unsubstituted hydroxy amine and/or aziridine products.
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申请公布号 |
US6008376(A) |
申请公布日期 |
1999.12.28 |
申请号 |
US19980138303 |
申请日期 |
1998.08.21 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
SHARPLESS, K. BARRY;GONTCHAROV, ALEXANDER V.;LIU, HONG |
分类号 |
C07D203/24;C07D203/26;(IPC1-7):C07D203/24 |
主分类号 |
C07D203/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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