发明名称 |
Antisense modulation of stearoyl-CoA desaturase expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
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申请公布号 |
US2005043256(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
US20030619253 |
申请日期 |
2003.07.15 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE ROSANNE;GRAHAM MARK J. |
分类号 |
A61K38/00;A61K45/06;C07H;C12N9/02;C12N15/113;(IPC1-7):A61K48/00;C07H21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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