发明名称 |
LYMPHANGIOGENESIS PROMOTER |
摘要 |
Described herein is the discovery that HGFs activate the growth and migration of lymphatic endothelial cells and thereby promote lymphangiogenesis. The present invention is based on this finding, and provides lymphangiogenesis-promoting agents comprising as active ingredients HGFs, or proteins or compounds functionally equivalent thereto. Based on the finding described above, the present invention also provides methods for promoting lymphangiogenesis which comprise the step of locally administering HGFs or proteins functionally equivalent thereto to affected areas in patients with lymphedema. |
申请公布号 |
EP1911459(A1) |
申请公布日期 |
2008.04.16 |
申请号 |
EP20060781920 |
申请日期 |
2006.07.28 |
申请人 |
ANGES MG, INC.;OSAKA UNIVERSITY |
发明人 |
MORISHITA, RYUICHI;KANEDA, YASUFUMI;NAKAGAMI, HIRONORI;SAITO, YUKIHIRO |
分类号 |
A61K38/22;A61K48/00;A61P7/10;C07K14/47;C12N15/09;C12P21/02;C12R1/91 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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