| 摘要 |
PROBLEM TO BE SOLVED: To provide a resveratrol derivative that generates hydrogen and exhibits keratin producing action, which is useful as a cosmetic, a food preparation, and a medicine, and which is, especially when used in cosmetic, expected to improve degradation of sebum, moisture holding power of skin, and resilience of skin, and to provide a method for producing the derivative.SOLUTION: Provided is a resveratrol derivative having a structure represented by the following formula (1) where four molecules of resveratrol are bonded, the resveratrol being obtained by subjecting a fermentation liquid to a protease treatment, followed by separation and purification by an ion exchange resin and the like, the fermentation liquid being obtained by adding Bacillus natto and Monascus purpureus to sprout-containing grape seeds and soybean powder and fermenting the mixture.EFFECT: The resveratrol derivative shows an amphiphilic property including hydrophobicity inside the molecule and hydrophilicity outside the molecule. The hydroxy group at 4-position of each resveratrol is free, and these hydroxy groups generate hydrogen, reduces cells, passes through cell membranes, activates genes of a keratin generating enzyme to increase production of keratin, suppresses decomposition of keratin, and activates proliferation of epithelial cells.SELECTED DRAWING: None |
