Formación de imágenes fluorescentes ópticas que utiliza colorantes cianina
摘要
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.
申请公布号
ES2575952(T3)
申请公布日期
2016.07.04
申请号
ES20070762058T
申请日期
2007.05.09
申请人
LI-COR, INC.
发明人
KOVAR, Joy;CHEN, Jiyan;DRANEY, Daniel R.;OLIVE, D. Michael;VOLCHECK, William M.;XU, Xinshe;LUGADE, Ananda G.;NARAYANAN, Narasimhachari