发明名称 |
METHOD FOR PREPARING TRANSGENIC NON-HUMAN MAMMALIAN ORGANS FOR TRANSPLANTATION TO HUMANS, AND NUCLEOTIDE SEQUENCES THEREFOR |
摘要 |
The use of nucleotide sequences coding for antibodies to any molecule involved in a graft versus host reaction (hereinafter anti-molecule antibodies), for preparing transgenic cells or organs of non-human mammals, wherein said molecules at least partially form immune complexes with said anti-molecule antibodies, such that the activity of said molecules in graft versus host reactions is at least partially inhibited, said transgenic cells or organs of non-human mammals being intended for transplantation into a patient, is disclosed. |
申请公布号 |
WO9803653(A2) |
申请公布日期 |
1998.01.29 |
申请号 |
WO1997FR01340 |
申请日期 |
1997.07.18 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA REC;VANHOVE, BERNARD;POURCEL, CHRISTINE;SOULILLOU, JEAN-PAUL |
发明人 |
VANHOVE, BERNARD;POURCEL, CHRISTINE;SOULILLOU, JEAN-PAUL |
分类号 |
A01K67/027;A61K35/76;A61K39/395;A61K48/00;A61P37/06;C07K16/28;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/13;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|