| 摘要 |
The invention relates to a stable drug form which is for oral administration and comprises: (a) a core comprising one or more active ingredients which are not to be released until after they have passed through the stomach, together with conventional pharmaceutical adjuvants, (b) an intermediate layer applied to the core, and (c) an external layer which is resistant to gastric juice. The intermediate layer in (b) is in the form of a reactive layer comprising a polymeric layered material which is partly neutralised with alkalis, is resistant to gastric juice and has cation-exchanger capacity. A process for the preparation of the stable drug form is also disclosed. |
