| 摘要 |
1,192,018. Dibenzoxazonines and dibenzthiazonines. E. R. SQUIBB & SONS Inc. 17 April, 1967 [29 April, 1966], No. 59311/69. Divided out of 1,192,016. Heading C2C. Novel dibenzoxazonines and dibenzthiazonines of the formula wherein R is H, R<SP>3</SP> and R<SP>4</SP> are each H, halogen, C 1-7 alkyl, C 3-7 cycloalkyl, CN, C 1-7 haloalkyl, C 1-7 alkoxy, C 1-7 alkylthio, C 1-7 alkylsulphinyl, C 1-7 alkylsulphonyl, C 1-7 haloalkoxy, C 1-7 haloalkylthio, sulphamoyl or N,N-di-(C 1-7 alkyl)- sulphamoyl; X is O or S; and n is 2, are prepared by cyclizing the corresponding 2-(2- aminophenethoxy)benzoic acids or 2-(2-aminophenethylmercapto) benzoic acids. 2 - (2 - Aminophenethoxy) benzoic acid is obtained by hydrolysing the corresponding ethyl ester resulting from the reduction of 2-(2-nitrophenethoxy) benzoic acid which is prepared by reacting ethyl salicylate with 2-nitrophenethyl bromide. |
