METHODS FOR INHIBITING CELL PROLIFERATION BY INHIBMETHODS FOR INHIBITING CELL PROLIFERATION BY INHIBITING THE MITOGENIC ACTIVITY OF MACROPHAGE MIGRATIITING THE MITOGENIC ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR ON INHIBITORY FACTOR
摘要
This invention is directed to methods of inhibiting cell proliferation by inhibiting the mitogenic activity of macrophage migration inhibitory factor ("MIF"). Inhibitory nucleic acids directed against MIF inhibit cell growth in both cells induced by growth factors and transformed (malignant) cells that express oncogenes.
申请公布号
WO9615242(A3)
申请公布日期
1996.08.08
申请号
WO1995US15000
申请日期
1995.11.16
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, RE;WISTOW, GRAEME, J.;PARALKAR, VISHWAS