发明名称 |
A DNA TRANSFER VECTOR, A MICROORGANISM MODIFIED BY SAID VECTOR AND THE SYNTHESIS OF A EUCARYOTIC PROTEIN BY THE MODIFIED MICROORGANISM |
摘要 |
A deoxyribonucleic acid (DNA) transfer vector is provided which comprises a nucleotide sequence coding for a eucaryotic protein joined to a procaryotic control fragment, the respective reading frames being in register, and the respective directions of transcription being the same. By connecting a eucaryotic gene to a gene for a protein normally compartmentalized or protected from intracellular degradation in some manner, the stability of a chimeric protein may by enhanced. A eucaryatic gene may be linked to a gene which has desirable genetic properties. In addition to the DNA transfer vector, the invention also provides a microorganism transformed by the transfer vector, a protein synthesised by such a microorganism, and a method of synthesising a protein. |
申请公布号 |
DE2966390(D1) |
申请公布日期 |
1983.12.15 |
申请号 |
DE19792966390 |
申请日期 |
1979.08.13 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
RUTTER, WILLIAM J.;GOODMAN, HOWARD M.;BAXTER, JOHN D. |
分类号 |
C12N15/09;A61K38/27;C07K14/005;C07K14/195;C07K14/575;C07K14/61;C07K14/62;C07K19/00;C12N1/20;C12P19/34;C12P21/02;C12R1/19;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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