LHRH antagonists similar to antide and congeners with higher water solubility have been synthesized by substitutions in positions 1, 5 or 6 with hydrophilic residues. These peptides have antiovulatory activity with minimal histamine releasing effect.
申请公布号
US5480969(A)
申请公布日期
1996.01.02
申请号
US19920946056
申请日期
1992.09.15
申请人
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
BOWERS, CYRIL Y.;FOLKERS, KARL A.;LJUNGQVIST, ANDERS;FENG, DONG-MEI;JANCEKA, ANNA
