发明名称 |
Combinatorial hydroxy-amino acid amide libraries |
摘要 |
Combination chemical libraries of Formula Iand methods for preparation are disclosed. The libraries allow one to screen large numbers of compounds for a desired biological activity with relative ease. The libraries may be tagged or untagged. In preferred libraries, Y is the residue of an N-acylated amino acid, a substituted 4-aminoproline or substituted piperazinealkanoic acid. The use of the libraries to discover biologically active compounds is also disclosed. |
申请公布号 |
AU5198698(A) |
申请公布日期 |
1998.05.29 |
申请号 |
AU19980051986 |
申请日期 |
1997.11.04 |
申请人 |
PHARMACOPEIA, INC. |
发明人 |
ROLLAND ELLWOOD DOLLE III;TAO GUO;THEODORE OTTO JOHNSON JR.;HITESH K. PATEL;SHIWEI TAO;ZHEN MIN HE |
分类号 |
C07D207/14;C07D207/16;C07D241/04 |
主分类号 |
C07D207/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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