| 发明名称 |
INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) IN GLAUCOMA TREATMENT |
| 摘要 |
FIELD: medicine, ophthalmology, medicinal biochemistry. ^ SUBSTANCE: invention relates to manufacturing ophthalmic composition used for reducing intraocular pressure. Invention proposes using inhibitors of glycogen synthase kinase-3. Proposed composition provides reducing intraocular pressure by increasing intraocular liquid efflux and to prevent loss of retina ganglion cells. ^ EFFECT: valuable medicinal properties of inhibitors. ^ 19 cl, 6 ex |
| 申请公布号 |
RU2297243(C2) |
申请公布日期 |
2007.04.20 |
| 申请号 |
RU20040112766 |
申请日期 |
2002.09.23 |
| 申请人 |
AL'KON, INK. |
发明人 |
KHELLBERG MARK R.;KLARK EHBBOT F.;PAN IOK-KHOU;KHELLBERG PEGGI EHLIZABET;MAKNATT LORETTA GREJVZ;VAN VAN'-KHEHN |
| 分类号 |
A61K38/43;C07D249/14;A61K9/00;A61K31/4015;A61K31/404;A61K31/4045;A61K31/4196;A61K31/426;A61K31/427;A61K31/4439;A61K31/55;A61K45/00;A61P3/10;A61P17/14;A61P25/00;A61P25/18;A61P25/24;A61P25/28;A61P27/06;A61P29/00;A61P43/00;C07D209/36;C07D209/40;C07D277/20;C07D277/42;C07D401/06;C07D403/04;C07D403/06;C07D405/06;C07D409/06;C07D417/06;C07D417/12;C07D487/04;C12N9/99 |
主分类号 |
A61K38/43 |
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