摘要 |
FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to a novel compound of 2-azethidinone substituted with sugar residue of the formula (III): . Also, invention relates to a method for decreasing cholesterol level by administration of pharmaceutical composition containing abovementioned compound and possessing hypocholesterolemic effect based on this compound of the formula (III) and containing the combination of compound of the formula (III) and, additionally, inhibitor of cholesterol biosynthesis. Also, invention relates to a method for treatment and prophylaxis of atherosclerosis or decreasing the cholesterol level. Invention provides preparing novel compounds possessing hypocholesterolemic activity. ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 10 cl, 3 tbl, 1 ex |