发明名称 SUGAR RESIDUE-SUBSTITUTED 2-AZETHIDINONES USEFUL FOR USING AS HYPOCHOLESTEROLEMIC PREPARATIONS
摘要 FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to a novel compound of 2-azethidinone substituted with sugar residue of the formula (III): . Also, invention relates to a method for decreasing cholesterol level by administration of pharmaceutical composition containing abovementioned compound and possessing hypocholesterolemic effect based on this compound of the formula (III) and containing the combination of compound of the formula (III) and, additionally, inhibitor of cholesterol biosynthesis. Also, invention relates to a method for treatment and prophylaxis of atherosclerosis or decreasing the cholesterol level. Invention provides preparing novel compounds possessing hypocholesterolemic activity. ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 10 cl, 3 tbl, 1 ex
申请公布号 RU2297422(C2) 申请公布日期 2007.04.20
申请号 RU20030122520 申请日期 2001.12.17
申请人 SHERING KORPOREJSHN 发明人 GOSAL ANIMA;ZBAJDA SHMUEL;CHAUDKHURI SVARAN K.;JANNUCHI ROBERT M.;FENG VENKING;OLTON KEVIN B.;PATRIK DZHEJMS E.;DEHJVIS KHARRI R.
分类号 C07H15/26;A61K31/366;A61K31/397;A61K31/70;A61K31/7052;A61K45/00;A61K45/06;A61P3/06;A61P9/10;A61P9/12;C07D205/08 主分类号 C07H15/26
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