| 摘要 |
1318963 1,2,3 - Benzo triazines FARBWERKE HOECHST AG 3 Aug 1970 [1 Aug 1969] 37320/70 Heading C2C A 3 - hydroxy - 4 - oxo - 3,4 - dihydro - 1,2,3- benzo triazine ester of a protected amino acid or a protected peptide, which is prepared from the free 3-hydroxy benzo triazine and a protected amino acid or peptide containing a free carboxyl group in the presence of a carbo diimide, is used in the preparation of peptides wherein a carboxylic ester of a protected amino acid or peptide is reacted with an amino acid or peptide having a free amino group and protecting groups are subsequently removed. The following starting materials are prepared. Z - Asn(Mbh)OH, Z - Gln(Mbh)OH and its methyl ester and H Gln(Mbh)OMe, HCl, Z-Gly- NH-MbH, and BOC-Leu-Phe-OH, where "Mbh" is 4,4<SP>1</SP>-dimethoxy benzhydryl. |
