PREPARATION OF METHYL ISOPROPYLIDENEAMINOOXYACETOXYACETATE

摘要

Process for preparing methyl isopropylideneaminooxyacetoxyacetate I I by reacting in an integrated process, without isolation of intermediates, a) acetone with hydroxylammonium sulfate and sodium hydroxide solution to give acetone oxime, the reaction being performed in the presence of toluene and/or the acetone oxime being extracted from the reaction mixture with toluene, b) treating the toluene solution thus obtained with sodium hydroxide solution and removing water, c) exchanging toluene for a dipolar aprotic solvent by distilla tion, d) reacting the crystal mash thus obtained with the sodium salt of chloroacetic acid to give the sodium salt of isopropylideneaminooxyacetic acid and then treating the reaction mixture with methyl chloroacetate and e) isolating the methyl isopropylideneaminooxyacetoxyacetate in a manner known per se.