N-ALKYL-SUBSTITUTED ATP DERIVATIVES AND METHOD OF PREPARATION THEREOF

摘要

FIELD: organic synthesis. SUBSTANCE: compounds of formula I (presented in description) are provided, wherein R and R , independently, are hydrogen or halogen atom; R and R , independently, are phenyl or C1-6-alkyl optionally substituted by one or several OR , C1-6-alkylthio, NR6R , COOR or halogen; R5,R6,R7 and R , independently, are C1-6-alkyl; and X is acid residue, and their pharmaceutically acceptable salts. Methods for preparing such compounds are also provided. Compounds I inhibit aggregation of platelets. EFFECT: extended choice of anticoagulation drugs. 9 cl, 1 tbl, 5 ex