| 发明名称 |
Lipoprotein associated phospholipase A2, inhibitors thereof and use of same in diagnosis and therapy |
| 摘要 |
<p>The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compunds which inhibit the enzyme.</p> |
| 申请公布号 |
EP0974663(A1) |
申请公布日期 |
2000.01.26 |
| 申请号 |
EP19990201834 |
申请日期 |
1994.06.24 |
| 申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
MACPHEE, COLIN HOUSTON;TEW, DAVID GRAHAM;SOUTHAN, CHRISTOPHER DAVID;HICKEY, DEIRDRE MARY B.;GLOGER, ISRAEL SIMON;LAWRENCE, GEOFFREY MARK P.;RICE, SIMON QUENTYN J. |
| 分类号 |
G01N33/53;A61K31/739;A61K38/00;A61K38/55;A61K39/395;A61P9/10;C07H21/04;C07K14/47;C07K16/40;C12N1/21;C12N9/16;C12N9/18;C12N9/20;C12N15/00;C12N15/09;C12N15/55;C12N15/74;C12P21/08;C12Q1/44;G01N33/573;(IPC1-7):C12N15/55 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
