| 摘要 |
PURPOSE:To obtain a new naphthoquinone derivative, having a high ability to grow bifidus bacteria and useful for foods, medicines, measurement, of the bifidus bacteria, etc., by using a microorganism such as the genus Propionibacterium capable of producing 2-amino-3-carboxy-1,4-naphthoquinone. CONSTITUTION:This new 2-amino-3-carboxy-1,4-naphthoquinone expressed by the formula is obtained by culturing a microorganism, belonging to the genera Propionibacterium, Enterobacter, Bacillus, etc., capable of producing 2-amino-3- carboxy-1,4-naphthoquinone (e.g. Propionibacterium freudenreichii ATCC6207 strain) in a culture medium, producing two kinds of naphthoquinones in the culture and collecting the resultant naphthoquinones. The obtained derivative has promoting actions on the growth of bifidus bacteria at an ultralow concentration and can be utilized as foods or medicines and further for improving enteral floras or an assay system, etc., for measuring the bifidus bacteria. |
