Ciclesonide-containing sterile aqueous suspension

摘要

A method of manufacturing a ciclesonide-containing sterile aqueous suspension comprising the step of sterilization by autoclaving a ciclesonide-containing aqueous suspension; wherein the concentration of ciclesonide after autoclaving is 95 % or more comparing to that before autoclaving; wherein the ciclesonide-containing aqueous suspension additionally contains hydroxypropylmethylcellulose. Also disclosed are aqueous suspensions prepared by the above method.