STORAGE STABLE TABLETS BASED ON BENZIMIDAZOLE DERIVATIVES COATED WITH A GASTRO-RESISTANT FILM

摘要

Moisture-resistant tablets containing as active principles benzimidazole derivatives and more specifically prazoles, comprising: a) a rapidly disintegrating core containing the active principle, b) a moisture-resistant rapidly disintegrating barrier layer, stabilizing and protecting of the core, applied by compression to the core (a) so as to completely envelop it, characterized in that all the operating steps for both core (a) and outer layer (b) preparation are undertaken in the dry state. Said tablet can be completely coated with a gastro-resistant film applied by conventional techniques.