发明名称 Cell analyzing apparatus and cell analyzing method
摘要 A cell analyzing apparatus includes: a first histogram acquiring section which is configured to acquire a first histogram of fluorescence intensities by using a result of a measurement of a number of nuclear stained cells; a second histogram acquiring section which is configured to acquire a second histogram that is normalized based on a fluorescence intensity value indicating a maximum value of the first histogram; a determining section which is configured to determine whether cancer cells exist or not, based on one of the first histogram and the second histogram; and an outputting section which is configured to output a result of the determination performed by the determining section.
申请公布号 US9443127(B2) 申请公布日期 2016.09.13
申请号 US201414488947 申请日期 2014.09.17
申请人 Nihon Kohden Corporation 发明人 Takeda Sunao;Kubo Hirotsugu;Shioyama Takahiro;Suzuki Akane;Nomura Kenichi;Kato Yo;Hinata Nae
分类号 G06K9/00;G01N21/64;G01N15/14;A61B5/00;G01N15/10 主分类号 G06K9/00
代理机构 Sughrue Mion, PLLC 代理人 Sughrue Mion, PLLC
主权项 1. A cell analyzing method comprising: acquiring a first histogram of fluorescence intensities by using a result of a measurement of a number of nuclear stained cells; determining whether the fluorescence intensity value indicating the maximum value of the first histogram is outside the predetermined range; in a case where a fluorescence intensity value indicating a maximum value of the first histogram is outside a predetermined range, determining that malignant tumor cells exist; in a case where the fluorescence intensity value indicating the maximum value of the first histogram is within the predetermined range, acquiring a second histogram that is normalized based on the fluorescence intensity value, and determining whether the malignant tumor cells exist or not; and outputting a result of the determination, wherein the acquiring the second histogram comprises performing normalization such that the maximum value of the first histogram has a first predetermined value and such that the fluorescence intensity value indicating the maximum value of the first histogram has a second predetermined value, wherein, when the fluorescence intensity value indicating the maximum value of the first histogram is determined to be outside the predetermined range, the determination that the malignant tumor cells exist is made without acquiring the second histogram, and wherein, when the fluorescence intensity value indicating the maximum value of the first histogram is determined to be within the predetermined range, the determination of whether the malignant tumor cells exist or not is made based on the second histogram.
地址 Tokyo JP