摘要 |
<p>Aryloxy- and arylthio-acetic acid derivs. Cpds. (I), useful as hypolipaemic and anti-inflammatory agents: (where R1 is 1-10C alkyl or benzyl; R2 is H or Me; R3 is H or alkyl; X is O or S) are prepd. by standard methods from the 20ols or 2-thiols through the dicarboxylic acids or nitriles or amides which cpds. also form part of the invention. Prefd. cpds. are the 2-heptanoic acids.</p> |