| 摘要 |
NEW MATERIAL:A glucofuranoside derivative (salt) expressed by formula I [Q<1> is H or benzyloxycarbonyl group; Q<2> is azido, (esterified) hydroxyl group, etc.; R is alkyl, aryl group, etc. (Q<2> is not azido group when Q<1> is H); R<3> is H or lower alkyl group; R<4> and R<5> are Hs or (OH-substituted) lower alkyl groups; R<6> and R<7> are (esterified) carboxyl groups, etc.; D and L are the configurations when the carbon atoms are asymmetric]. EXAMPLE:Benzyl 2,6-diamino-2,6-dideoxy-3-0-(D-2-propionyl-L-alanyl-D-isoglutamine)-be ta-D-glucofuranoside. USE:An immune function enhancer and an intermediate for a glucosamine derivative (salt). PROCESS:A compound of formula II is condensed with a compound of formula III [R<4>' and R<5>' are Hs, (OH-substituted) alkyl groups, etc.], and if necessary subiected to deprotection to give the objective derivative. |
