Capillary array confocal fluorescence scanner and method

摘要

A laser-excited capillary array scanner including a plurality of capillaries having a parallel, side-by-side, coplanar relationship and a laser-excited confocal fluorescence detector for detecting fluorescence from selected interior volumes of each of the capillaries sequentially and repetitively during electrophoresis or other separation method. The invention also relates to a method of analyzing a plurality of capillaries, with a single scanner, by scanning a plurality of capillary passages in side-by-side relationship, and periodically and repetitively detecting fluorescence from each capillary passage during electrophoresis or other separation method.