摘要 |
The present invention discloses compositions containing naturally secreted human extracellular matricies, the methods of making those matricies, and the method of using those matricies. The extracellular matrix is obtained by growing cells into a three-dimensional support structure so that the cells secrete an extracellular matrix. Next, the cells are killed and removed from the support structure leaving only the extracellular matrix on the support structure. The extracellular matrix can then be removed from the support, combined with a suitable pharmacologically acceptable carrier and injected into a tissue defect area in the skin of a patient.
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