| 摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes a new compound - 1-hydroxy-2-naphthalenecarboxylate of 4-hydroxy-<EMI ID=0.386 HE=3 WI=3 TI=CHI>-[[[6-(4-phenylbutoxy)hexyl] amino] methyl]-1,3-benzenedimethanol (salmeterol xinafoate) as easily fluidized crystalline form and exhibiting controlled particle size from 1 to 10 microns and dynamic volume density less 0.1 g x cm that can be used for preparing a pharmaceutical compound with an acceptable carrier. Invention describes also a pharmaceutical composition that can be used for inhalation and containing the above indicated compound. The composition is easy for using and can be fluidized easily. EFFECT: improved quality and properties of the composition. 9 cl, 48 dwg, 6 tbl, 14 ex
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