Novel process for producting imidazo[1,2-b]pyridazine derivative

摘要

A process for easily and inexpensively producing an imidazo[1,2-b]pyridazin-3-ylsulfonamide derivative which has a substituent bonded to the 6-position carbon atom and is represented by the formula (II): (wherein R represents lower alkyl, lower cycloalkyl optionally substituted by lower alkyl, lower alkenyl, or lower alkynyl), the process comprising reacting an imidazo[1,2-b]pyridazine compound represented by the formula (I): (wherein X represents halogeno or lower alkyl optionally substituted by halogeno; Y represents hydrogen or SO₂N-CH-NR¹R²; and Z represents halogeno or OSO₂R³) with an organometallic compound in the presence of a transition metal catalyst. The derivative is useful as an intermediate for herbicides.