| 摘要 |
The invention relates to a compound having general formula (I), wherein R1 denotes a phenyl or naphthalenyl group which is optionally substituted by one or more halogen atoms or groups hydroxy, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, trifluoromethyl, trifluoromethoxy, benzyloxy, C3-6-cycloalkyl-0- or C3-6-cycloalkylC1-3-alcoxy; R2 denotes (i) a group having general formula CHR3CONHR4, wherein R3 denotes a hydrogen atom or a methyl group and R4 denotes a hydrogen atom or group C1-3-alkyl, C3-5- cycloalkyl or (pyridin-4-yl)methyl, (ii) a 2,2,2-trifluoroethyl group, (iii) a (imidazol-2-yl)methyl group, (iv) a (benzimidazol-2-yl) methyl group or (v) a phenyl group which is optionally substituted by one or more halogen atoms or groups cyano, nitro, C1-3-alkyl, C1- 3-alkoxy, trifluoromethyl or trifluoromethoxy; and n dentoes a number between 1 and 3, said compound taking the form of a base, an acid addition salt, a hydrate or a solvate. The invention can be used in therapeutics. |
