摘要 |
The present invention relates to novel 2-heteroaryl substituted indole de rivatives, precursors thereof, and therapeutic uses of such compounds, havin g the structural formula (Ia) below: and to their pharmaceutically acceptabl e salt, compositions and methods of use. Furthermore, the invention relates to novel 2-heteroaryl substituted indole derivatives that are suitable for i maging amyloid deposits in living patients, their compositions, methods of u se and processes to make such compounds. More specifically, the present inve ntion relates to a method of imaging amyloid deposits in brain in vivo to al low antemortem diagnosis of Alzheimer's disease as well as measureing clinic al efficacy of Alzheimer?s disease therapeutic agents.
|