TETRAHYDROPYRROLOTHIAZINE COMPOUNDS

摘要

The present invention provides compounds of Formula I for use in the treatment or prevention of the progression of Alzheimer's disease; (see formula I) wherein A is (a), (b), (c) or (d), R1 is H or F; R2 is H,¨CH2OH or C1-C3 alkyl, (e) or (f); R3 is H, F, or CN; R4 is H,F; or CN; and R5 is H, ¨ CH3 or ¨OCH3; or a pharmaceutically acceptable salt thereof. (see formula a) (see formula b) (see formula(c) (see formula d) (see formula e) (see formula f)