发明名称 |
ANTI-THYMOSIN .ALPHA.1 MONOCLONAL ANTIBODY-PRODUCING HYBRIDOMA |
摘要 |
There are disclosed a hybridoma obtained by fusing a myeloma cell with an anti-thymosin .alpha.1 antibody-producing cell and selecting a hybridoma which produces a monoclonal antibody that recognizes the N-terminus of thymosin .alpha.1; an antithymosin .alpha.1 monoclonal antibody which is produced by the hybridoma, and a method for measuring thymosin .alpha.1 which comprises forming a three-component complex comprising thymosin .alpha.1, the anti-thymosin .alpha.1 monoclonal antibody (A), and an anti-thymosin .alpha.1 antibody (B) that recognizes a different site of thymosin .alpha.1 than antibody (A) does; forming a fourcomponent complex of said three- component complex with a labeled substance (C) that specifically binds to antibody (A) or antibody (B) of the three-component complex; and detecting the labeled substance in said four-component complex.
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申请公布号 |
CA2145905(A1) |
申请公布日期 |
1996.03.10 |
申请号 |
CA19952145905 |
申请日期 |
1995.03.30 |
申请人 |
YUKA MEDIAS CO., LTD. |
发明人 |
YOKOI, HIROYUKI;SAITO, TAKAO;OHNO, HIDETO |
分类号 |
G01N33/53;C07K16/00;C07K16/18;C07K16/26;C07K19/00;C12N5/10;C12N15/02;C12P21/08;C12R1/91;G01N33/577;(IPC1-7):C12N5/18;G01N33/566;G01N33/74 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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