| 摘要 |
<p>(A) 3,1-Benzothiazines and 3,1-benzoxazines of gen. formula (I), where A = O or S R = H, alkyl, cycloalkyl, alkenyl, cycloalkenyl aryl, aralkyl, or lower dialkylaminoalkyl in which the dialkylamino group can also be cyclized via O, S, or methyl- or benzylimino, R1 = H, halogen, methoxy, CF3, NO2 R2 = alkyl, aralkyl, or aryl, in which the benzene rings of the last two can be substituted by halogen, methoxy, CF3, NO2. (B) Salts of I formed with organic and inorganic acids. Compounds (1) combine valuable pharmacological properties with very low toxicity. They are central depressants, as well as stimulants, sedatives, noradrenaline potentiators, analgesics and spasmolytics, and they prolong narcosis. They are useful in the treatment of mental diseases, e.g. depression, psychioneuroses, disturbances and anxiety states of neurotic and psychotic patients.</p> |
