Monomeric collagen is oriented in solution and the orientation is retained in the resulting gel by setting up convective flow paths in the solution during gelation. The convection is induced by uniform peripheral heating of the cold, collagen solution in a small-diameter cylinder. Oriented collagen produced in this manner has excellent wet strength for use in implants for natural reconstruction of body collagen.
申请公布号
DE3380027(D1)
申请公布日期
1989.07.13
申请号
DE19833380027
申请日期
1983.07.18
申请人
BATTELLE DEVELOPMENT CORPORATION
发明人
FINK, DAVID, J.;HUGHES, KENNETH, E.;HUTSON, TIMOTHY, B.