| 摘要 |
<p>Pharmaceutical composition comprising microparticles having an average diameter ranging from 40 to 150 nm, consisting of one or more lipids, a drug and, optionally, a steric stabilizer, suitable to the transmucosal passage and to the overcoming of the blood-brain barrier and the blood-cerebrospinal fluid barrier, said microparticles being obtained dispersing in an aqueous medium cooled to 2-4 °C an oil/water or a water/oil/water microemulsion comprising said constituents.</p> |
