摘要 |
A compound of formula (I): or a salt, solvate or physiologically functional derivative thereof for use as a IK and/or SK channel opener. Methods of screening SK ion channels, particularly SK1 and medicaments for the treatment of a urinogenital, respiratory, cardiovascular, neuronal disorder, of sleeping disorders, sickle cell anemia, pain, inflammation and bowel disease (IBD) are also disclosed.
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申请人 |
GLAXO GROUP LIMITED;COX, BRIAN;CRYAN, JENNIFER, ELIZABETH;DALE, TIMOTHY, JAMES;ROBERTSON, GRAEME, MICHAEL;TREZISE, DEREK, JOHN |
发明人 |
COX, BRIAN;CRYAN, JENNIFER, ELIZABETH;DALE, TIMOTHY, JAMES;ROBERTSON, GRAEME, MICHAEL;TREZISE, DEREK, JOHN |