Process for producing alkyl 4-(alkoxy methyl phosphinoyl)butyrates and alkyl-(2-amino-4-(alkoxy methyl phosphinoyl)) butyrates.

摘要

Dialkyl 4-methylphosphinobutyrates represented by the following general formula; (wherein R1 represents hydrogen atom or acylamino group, and R2 and R5 each represents C1-C5 alkyl group) are intermediates for D,L-2-amino-4-methylphosphinobutyric acid useful as a herbicide, and are prepared by reacting a corresponding vinylacetic acid ester with methylphosphorous acid monoalkyl ester at 100-200 DEG C in the presence of a radical-generating agent or under irradiation with ultraviolet rays.