Process for preparing 3-chloro-6-(2-hydroxyphenyl)-pyridazines

摘要

A process for preparing 3-chloro-6-(2-hydroxyphenyl)pyridazines by the reaction of 6-(2-hydroxyphenyl)-3(2H)-pyridazinones with phosphorus oxychloride and a disubstituted formamide. The chloropyridazine compounds are useful intermediates for preparing compounds which have beta -adrenergic blocking and vasodilator activity and are useful as antihypertensive agents.