摘要 |
Object: to provide compounds having an inhibitory effect on the production of inflammatory cytokines. Constitution: compounds having general formula (I), pharmacologically acceptable salts thereof or derivatives of the same, wherein A: single bond, oxygen, sulfur, CO, SO, SO2, C(R<9>)(R<10>) ÄR<9>, R<10>: H, OH, halogeno, alkylÜ, N(R<11>), C=NOR<11> ÄR<11>: H, alkylÜ; D: single bond, C(R<12>)(R<13>) ÄR<12>, R<13>: H, OH, halogeno, alkylÜ; R<1> : optionally substituted pyridyl; R<2> : optionally substituted phenyl; R<3> : halogeno, alkyl, haloalkyl, alkoxy, haloalkoxy; R<4>, R<5>, R<6>, R<7>, R<8> : H, alkyl; k: 0-3; and m: 1, 2. |