Anti-inflammatory eyedrops comprising: (a) 0.05 to 0.7 w/v % of diclofenac sodium; (b) 1 to 10 w/v % of gamma -cyclodextrin; (c) 1 to 20 w/v % of polyvinylpyrrolidone; and (d) 0.002 to 0.01 w/v % of benzethonium chloride, or 0.002 to 0.005 w/v % of benzalkonium chloride; and having a pH value of 7.0 to 8.5. The eyedrops contain diclofenac sodium at a concentration over a wide range, remain stable for a long period of time, and little irritate the eyes.