发明名称 COMPOUNDS WITH COMBINED CALCIUM CHANNEL BLOCKER AND beta-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITIES FOR TREATMENT OF HEART DISEASE
摘要 The present invention provides compounds possessing inhibitory activity against beta-adrenergic receptors and L-type calcium channels. The present invention further provides pharmaceutical compositions comprising such compounds, methods of preparing such compounds, and methods of using such compounds for regulating calcium homeostasis, for treating a disease, disorder or condition in which disregulation of calcium homeostasis is implicated, and for treating hypertension, cardiovascular disease, congestive heart failure, myocardial ischemia, cardiomyopathies, stroke or epilepsy.
申请公布号 WO2005016885(A2) 申请公布日期 2005.02.24
申请号 WO2004US26326 申请日期 2004.08.16
申请人 ARTESIAN THERAPEUTICS, INC.;HAMILTON, GREGORY, S. 发明人 HAMILTON, GREGORY, S.
分类号 A61K31/4422;A61P9/00;C07D211/90;C07D401/12 主分类号 A61K31/4422
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