| 发明名称 |
Method for enhancing somatic hypermutation, gene conversion and class switch recombination |
| 摘要 |
<p>The invention relates to a method for enhancing somatic hypermutation, gene conversion and/or immunoglobulin class switch recombination in a cell by increasing the level of an E2A encoded protein in the cell. The invention also relates to cells and cell lines with an increased level of said activities.</p> |
| 申请公布号 |
EP1780272(A1) |
申请公布日期 |
2007.05.02 |
| 申请号 |
EP20050023503 |
申请日期 |
2005.10.27 |
| 申请人 |
GSF-FORSCHUNGSZENTRUM FUER UMWELT UND GESUNDHEIT GMBH |
发明人 |
BUERSTEDDE, JEAN-MARIE, DR.;SCHOETZ, ULRIKE |
| 分类号 |
C12N15/00 |
主分类号 |
C12N15/00 |
| 代理机构 |
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| 地址 |
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