Quinoline compounds which are anti-angiogenic integrin alpha5 beta1 inhibitors for use in the treatment of fibrosis or fibrosis-related diseases

摘要

A new medical therapy, and more particularly certain quinoline compounds which are anti-angiogenic integrin aplha5beta1 inhibitors, for use in the treatment of fibrosis, or a fibrosis-related disease, such as a fibrotic disease affecting the lung, liver, kidney, skin, epidermis, endodermis, muscle, tendon, cartilage, heart, stomach, large intestine, small intestine, colon, uterus, nervous system, testis, adrenal gland, artery, vein, biliary tract, or eye.

主权项

1. A method for the treatment of fibrosis, or a fibrosis-related disease, whereby a therapeutically effective amount of a compound which is 4-[(4-methoxyphenyl)-amino]-6-(methylcarbamoyl)quinoline-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, is administered to a patient in need of such treatment.