发明名称 |
SIDE CHAIN UNSATURATED 1 ALPHA-HYDROXYVITAMIN D HOMOLOGS |
摘要 |
This invention provides novel vitamin D-related compounds characterized by extended unsaturated side chain structures. Such compounds exhibit increased activity in arresting the proliferation and promoting the differentiation of malignant cells with only minimal calcemic activity and thus represents new therapeutic agents applicable and uniquely useful in differentiation therapy of malignant diseases. The activity characteristics of these compounds provide the basis of a method for the treatment of neoplastic diseases, specifically leukemoid diseases. |
申请公布号 |
AU3553389(A) |
申请公布日期 |
1989.11.24 |
申请号 |
AU19890035533 |
申请日期 |
1989.04.18 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
HECTOR F. DELUCA;HEINRICH K. SCHNOES;KATO L. PERLMAN |
分类号 |
A61K31/59;A61K31/593;A61P35/00;C07C401/00;C07F7/18 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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