PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-1 RECEPTOR

摘要

Peptides that bind to the interleukin-1 type I receptor (IL-1RtI) can be used to assay the amount of IL-1R, or an IL-1R agonist or antagonist, in a sample and comprise a sequence of amino acids selected from the group consisting of: (1) WXXXGZ1W; (2) XXQZ5YZ6XX and (3) Z23NZ24SZ25Z26Z27Z28Z29Z30L. Also provided are peptides which bind to the IL-1RtI, which are 11 to 40 amino acids in length, which comprise the core sequence of amino acids Z31XZ41Z32Z34Z36Z42Z37Z38.