DITHIANE-BASED COUPLING PROCEDURES AND PRODUCTS THEREOF
摘要
The unsymmetrical linchpin coupling of 2-t-bityldimethylsilyl-1,3-dithiane with two electrophiles has been achieved as a single operation via solvent-controlled Brook rearrangement. The new protocol has also been extended to five-component couplings which should greatly facilitate the total synthesis of complex polyene natural products.
申请公布号
WO9838185(A1)
申请公布日期
1998.09.03
申请号
WO1998US04073
申请日期
1998.02.27
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;SMITH, AMOS, B.;BOLDI, ARMEN
