发明名称 Biphenyl derivatives
摘要 This invention provides biphenyl derivatives of formula I: wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, W, a, b and c are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The biphenyl derivatives of this invention possess both beta<SUB>2 </SUB>adrenergic receptor agonist and muscarinic receptor antagonist activity and therefore, such biphenyl derivatives are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
申请公布号 US2006223858(A1) 申请公布日期 2006.10.05
申请号 US20060448293 申请日期 2006.06.07
申请人 MAMMEN MATHAI;HUGHES ADAM;CHEN YAN 发明人 MAMMEN MATHAI;HUGHES ADAM;CHEN YAN
分类号 A61K31/445;A61K31/452;A61K31/4709;C07D211/46;C07D211/48;C07D211/54;C07D211/56;C07D211/58;C07D401/06;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/06;C07D409/12;C07D409/14;C07D453/02;C07D471/08;G01N33/94 主分类号 A61K31/445
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