发明名称 |
LENTIVIRAL VECTOR-BASED JAPANESE ENCEPHALITIS IMMUNOGENIC COMPOSITION |
摘要 |
The present invention relates to a lentiviral vector-based Japanese encephalitis (JE) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prM) and the envelope (E) protein, in particular glycoprotein of a Japanese encephalitis virus (JEV) or immunogenic fragments thereof. The present invention also provides cells expressing the lentiviral vector, uses and methods to prevent a JEV infection in a mammalian host, especially in a human or an animal host, in particular a pig or a piglet, preferably a domestic pig or a domestic piglet. |
申请公布号 |
WO2016091836(A1) |
申请公布日期 |
2016.06.16 |
申请号 |
WO2015EP78891 |
申请日期 |
2015.12.07 |
申请人 |
INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
CHARNEAU, PIERRE;DESPRES, PHILIPPE;DE WISPELAERE, MELISSANNE;SOUQUE, PHILIPPE;FRENKIEL, MARIE-PASCALE |
分类号 |
C12N15/86;A61K35/76;A61K39/00;C07K14/18 |
主分类号 |
C12N15/86 |
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