发明名称 ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXIDANTS
摘要 FIELD: medicine. SUBSTANCE: claimed invention describes compounds of formula I: HN-(CH)-A-(CH)-O-NH(I) and salts thereof, wherein A represents C-Ccycloalkylene; n is O or 1, and independently of n, m is 0 or 1; provided that (a) distance between aminooxy radical HN-O- and amino group -NHis equal to at least 3, but not more 4 carbon atoms and that (b) two radicals HN-(CH)and (CH)-O-NHare not attached to the same carbon atom of radical A. Compounds of formula I and salts thereof are ornitine decarboxylase inhibitors. EFFECT: improved properties of the title compounds.
申请公布号 RU95110887(A) 申请公布日期 1996.10.27
申请号 RU19950110887 申请日期 1995.01.11
申请人 TSIBA-GEJGI AG 发明人 JORG FRAJ;JAROSLAV STANEK
分类号 A61K31/13;A61P33/02;A61P35/00;A61P43/00;C07C239/08;C07C239/20 主分类号 A61K31/13
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